Medical Bottle Stopper Laboratory
Product name: rubber stopper butyl
Size: 13mm 20mm customized
Material: IIR, silicone
Color: gray, any color
Feature: Eco-friendly
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Full Customization
Description
Product name: rubber stopper butyl
Size: 13mm 20mm customized
Material: IIR, silicone
Color: gray, any color
Feature: Eco-friendly
Product name: aluminum-plastic flip off cap
Size: 13mm 20mm customized
Material: aluminum, plastic
Color: green, white, blue
Feature: Eco-friendly
How to seal drug injection bottles? Aluminum-plastic caps play a big role in injection bottle packaging materials. Today we will introduce the classification and structural dimensions of aluminum-plastic caps.
The color of the exterior can be a variety of colors, and the design surface is smooth or rough as needed
You can also further customize the company's logo, patterns, and product names
These are all workable; it mainly depends on the needs of the customer
Butyl Rubber Stopper · Full Size Range
Laboratory Grade Rubber Bottle Stoppers
Butyl rubber stopper for injection glass vial · 10ml · 20ml · 50ml · 100ml · 150ml · laboratory grade
Butyl Rubber Stopper
10ml – 150ml Range
For Injection Glass Vials · Laboratory Grade Rubber Bottle Stoppers
One elastomer, five vial sizes · consistent material spec across the full injection vial range
|
10ml 20mm stopper |
20ml 20mm stopper |
50ml 20/28mm stopper |
100ml 28/32mm stopper |
150ml 32mm stopper |
lab grade available |
|
5 sizes 10-150ml range |
bromobutyl elastomer |
20/28/32mm closure sizes |
|
lab grade available |
pharma grade available |
USP <381> Test basis |
10ml to 150ml - one product family, five volumes
The butyl rubber stopper range covers the full small-to-mid injection vial spectrum - from single-dose 10ml presentations to 150ml multi-dose and bulk formats - built from the same elastomer specification and quality system across every size, so switching between vial volumes in your product line does not mean switching material suppliers or requalifying a new compound.
Why one elastomer family across five sizes matters
When your product line spans multiple vial volumes - say a 10ml single-dose presentation alongside a 100ml bulk format of the same drug product - using the same bromobutyl compound across both means a single material qualification, a single set of extractables/leachables data, and a single supplier relationship to manage, rather than re-validating a different elastomer for each size. The stopper geometry (height, cavity engagement, compression ratio) scales appropriately to each vial size while the underlying material specification stays constant.
From single dose to bulk - where each size is used
Each volume in the range corresponds to common pharmaceutical, laboratory, and veterinary use cases - the stopper specification adapts to the closure size required at each point in the range.
10-20ml
Single & small multi-dose injectables
20mm closure · peptide, vaccine, small biologics
The 10ml and 20ml sizes cover the most common single-dose and small multi-dose injectable presentations - peptide products, small-volume vaccines, and concentrated biologics where only a small fill volume is required per vial.
✓ 20mm standard closure size
✓ Peptide and small-volume biologics fit
50ml
Mid-volume injectable & veterinary
20mm or 28mm closure · transition size
The 50ml size sits at the transition point between small-dose and bulk presentations - commonly used for veterinary injectables, mid-volume human biologics, and laboratory reagent storage requiring a moderate working volume.
✓ 20mm or 28mm closure depending on neck finish
✓ Common veterinary and lab reagent format
100-150ml
Bulk & large multi-dose presentations
28mm or 32mm closure · bulk supply, lab reagents
The 100ml and 150ml sizes serve large multi-dose vaccine and biologics presentations, bulk laboratory reagent and buffer storage, and veterinary bulk-dispense applications - where higher fill volume per container reduces per-dose packaging overhead.
✓ 28mm or 32mm larger closure size
✓ Bulk reagent & large multi-dose use
Laboratory grade - what's different from pharma grade
Laboratory grade rubber stoppers use the same bromobutyl elastomer base but are produced and documented to a lighter qualification standard than full pharmaceutical injectable grade - appropriate for research, reagent storage, and non-injectable laboratory applications where the strictest pharmacopoeial documentation isn't required.
material
+
-
Same elastomer base
Bromobutyl rubber · consistent compound
Laboratory grade stoppers use the same bromobutyl rubber compound as pharmaceutical grade - the difference is in documentation and qualification level, not the underlying material chemistry. Sealing performance, compression behaviour, and chemical resistance are functionally equivalent.
documentation
+
-
Lighter documentation package
No full USP <381> battery required
Laboratory grade supply typically includes a basic certificate of conformity and dimensional data, but does not carry the full USP <381> biological reactivity testing battery, extractables/leachables study, or cleanroom production certification required for injectable pharmaceutical use. This significantly reduces cost for non-patient-contact applications.
use case
+
-
Research & reagent applications
Non-injectable · research · reagent storage
Appropriate for research laboratory reagent bottles, buffer storage, sample vials, and other non-injectable laboratory applications where pharmacopoeial-grade documentation is not required by your protocol or regulatory pathway
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-
Confirm which grade your application requires
If your product will contact a drug substance intended for human or animal injection, pharmaceutical injectable grade with full USP <381> documentation is required - laboratory grade is not a substitute. Laboratory grade is appropriate for research, QC testing, reagent storage, and other non-patient-contact uses. Tell us your intended application and we will confirm the correct grade and supply the appropriate documentation package.
Full range specification - 10ml to 150ml reference table
Reference specifications across the complete butyl rubber stopper size range for injection glass vials.
| Vial volume | Stopper size | Typical use | Grade options | Material |
|---|---|---|---|---|
| Small format - single & small multi-dose | ||||
| 10ml | 20mm | Single-dose injectable, peptide | Lab / Pharma | Bromobutyl |
| 20ml | 20mm | Small multi-dose, vaccine | Lab / Pharma | Bromobutyl |
| Mid format - transition volume | ||||
| 50ml | 20mm / 28mm | Veterinary, mid-volume biologics, lab reagent | Lab / Pharma | Bromobutyl |
| Large format - bulk & multi-dose | ||||
| 100ml | 28mm / 32mm | Large multi-dose, bulk lab reagent | Lab / Pharma | Bromobutyl |
| 150ml | 32mm | Bulk supply, veterinary bulk-dispense | Lab / Pharma | Bromobutyl |
Stopper size depends on your specific vial neck finish
The closure sizes shown are the most common pairing for each volume, but actual stopper size depends on your specific vial's neck finish, not strictly its fill volume - some 50ml vials use 20mm necks, others use 28mm. Confirm your exact vial neck finish (or send a sample) and we will match the correct stopper dimension regardless of fill volume.
who orders this range
top service industries
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Pharmaceutical manufacturers
Multi-SKU product lines · 10–150ml
Manufacturers with product lines spanning multiple vial volumes - using one elastomer family across all SKUs to simplify qualification and supplier management.
Veterinary pharmaceutical producers
50ml–150ml bulk veterinary formats
Veterinary pharmaceutical producers filling larger-volume vials for livestock and companion animal injectables - using the mid-to-large size range of the stopper family.
Research laboratories
Lab grade · reagent & buffer storage
Research laboratories using laboratory-grade stoppers for non-injectable reagent storage, buffer solutions, and sample vials across multiple bottle sizes within their workflow.
CDMOs & fill-finish
Multi-client multi-volume production
Contract fill-finish organisations running multiple client products across different vial volumes - sourcing the complete size range from one supplier for consistent stopper quality.
Biotech & clinical supply
Range from dose-finding to bulk drug substance
Biotech clinical supply teams needing different vial volumes across their development pipeline - from small-volume dose-finding studies to bulk drug substance storage - with consistent elastomer qualification across all sizes.
Packaging component distributors
B2B · full size range stocked
Pharmaceutical and laboratory component distributors stocking the complete 10ml–150ml stopper range in both laboratory and pharmaceutical grades.
One Elastomer. Five Volumes.
10ml through 150ml, from one supplier.
Request a sample set across the full 10ml–150ml range, or tell us your specific vial volume and neck finish for a single-size quote. Laboratory grade and pharmaceutical injectable grade both available.
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