Pharmaceutical Rubber Stopper
Product Name: Rubber stopper
Specifications: 13mm 13-A
Material: Butyl rubber
Color: Grey or customized
Productivity: 1000000 pcs/day
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Full Customization
Description
HIGH - TEMPERATURE RESISTANT VIAL BUNGS
EMBOSSED LOGO · 20MM CRIMP · MEDICAL GRADE
Pharmaceutical rubber stoppers · high-temperature resistant vial bungs · embossed logo 20mm crimp
Pharmaceutical Rubber Stoppers
High-Temperature Resistant
Vial Bungs · Embossed Logo Seal · 20mm Crimp · Medical Grade
Autoclave-stable elastomer · 121°C+ sterilisation · custom embossed 20mm cap
|
121°C+ Autoclave rated |
High-temp Elastomer grade |
Embossed 3D raised logo |
20mm Crimp size |
Medical grade Certification |
Bromobutyl Base elastomer |
Built for heat - autoclave and process temperature survival
Pharmaceutical rubber stoppers are routinely exposed to high-temperature steam sterilisation before use - standard autoclave cycles operate at 121°C, with extended cycles reaching 134°C. The stopper elastomer must survive these temperatures without losing its dimensional accuracy, sealing geometry, or elastic recovery properties.
2-8°C
Cold chain storage
Refrigerated product storage
Standard refrigerated storage temperature for the filled vial post-sterilisation. All stopper grades perform normally at this range - included for full temperature envelope reference.
~80°C
Process / depyrogenation heat
Pre-sterilisation processing
Some fill-finish processes expose components to moderate heat during washing, drying, or pre-sterilisation handling. Standard pharmaceutical-grade elastomers handle this range without issue.
121°C ★
Standard steam autoclave
USP/EP standard sterilisation cycle
The standard moist-heat steam sterilisation cycle for terminal sterilisation of filled vials. High-temperature resistant stoppers maintain full dimensional and sealing integrity through repeated cycles at this temperature.
134°C
Extended / rapid sterilisation cycle
High-temp resistant grade required
Extended or rapid sterilisation programmes used in some manufacturing protocols reach higher temperatures with shorter hold times. Only the high-temperature resistant elastomer formulation reliably maintains stopper geometry and seal performance at this upper range.
Dimension
+
-
Dimensional stability under heat
No softening, swelling, or distortion
High-temperature resistant bromobutyl formulations are compounded to resist thermal softening and dimensional swelling during repeated autoclave exposure - the stopper's cavity-engaging geometry, compression ratio, and crimp-fit dimensions remain within tolerance after sterilisation, exactly as specified before the heat cycle.
✓ No swelling or softening at 121–134°C
✓ Crimp-fit dimensions maintained post-autoclave
✓ Compression ratio preserved through cycles
Recovery
+
-
Elastic recovery retained after heat exposure
Sealing force maintained post-sterilisation
The vulcanised cross-link network of the high-temperature grade is formulated to resist thermal degradation of cross-link density - meaning the stopper's elastic recovery and compression set resistance properties (the basis of its sealing function) are preserved after sterilisation, not just its visible shape.
✓ Cross-link density stable through heat exposure
✓ Compression set resistance preserved
✓ Sealing force maintained post-sterilisation
Repeated
+
-
Repeated cycle tolerance
Multiple autoclave runs · cumulative stability
Some fill-finish protocols require multiple sterilisation passes or revalidation cycles. The high-temperature resistant grade is formulated and tested for cumulative thermal exposure tolerance - not just single-cycle survival - supporting process flexibility without re-qualifying the stopper at every cycle change.
✓ Multi-cycle thermal exposure tested
✓ Cumulative stability data available
✓ Suitable for revalidation protocols
Standard bromobutyl vs high-temperature resistant grade
Standard bromobutyl formulations are perfectly suitable for single-cycle 121°C sterilisation in most applications. The high-temperature resistant grade uses an optimised cross-linking system and stabiliser package specifically formulated for extended (134°C) cycles, repeated sterilisation passes, or processes with longer high-temperature hold times - confirm your specific sterilisation protocol at order so the correct elastomer grade is supplied.
Wholesale company making embossing seal with customized LOGO for bottles of 20mm crimp open for medical grade
Company making embossing flip tops with custom logo, 3D convex customized logo stamp on flip-off caps injectable vial top 20mm, personalized with embossed words flip tops 20mm crimp flip top, 20mm custom logo cap seals for steriod vials, raised logo made wholesale company pharma glass bottle caps
Custom embossing - 20mm crimp seal
Embossed seal with custom logo - 20mm crimp, medical grade
Embossing creates a genuinely three-dimensional raised (or recessed) logo on the aluminum crimp cap surface - formed by mechanically deforming the metal itself during the capping production process, rather than applying ink or foil on top of a flat surface. The result is a tactile, permanent brand mark that catches light differently from every angle.
3D Raised
Three-dimensional raised relief
Mechanically formed · not printed
The logo or symbol is formed by a die that physically presses the aluminum into a raised (or recessed) profile during cap manufacturing - the metal itself takes the shape of your logo. This produces a permanent, tactile mark that cannot wear off, fade, or be removed by abrasion, unlike printed ink which sits on the surface and can scratch away.
20mm
20mm crimp cap compatibility
Standard vial neck finish
Embossing is available on the 20mm crimp cap format - the standard closure size for many vaccine, biologics, and pharmaceutical vial presentations. The emboss die is custom-tooled to your logo artwork and integrated into the standard 20mm cap production tooling.
medical grade
Medical grade material & process
Pharma-compliant aluminum + lacquer
The embossed cap uses the same medical-grade aluminum alloy and product-contact-safe lacquer as a standard pharmaceutical crimp cap - embossing changes the surface geometry, not the material safety profile. Fully compatible with standard crimping equipment and pharmaceutical packaging compliance requirements.
Embossing vs printing - when to choose embossing
Printing applies colour and can render fine detail, gradients, and multi-colour logos - embossing is monochrome (the metal's own colour) but provides a permanent, premium tactile mark immune to wear. Many pharmaceutical and peptide brands combine both: a printed colour design plus an embossed brand symbol or anti-counterfeit mark, giving visual richness and a permanent tactile authentication feature in the same cap.
What to provide for a custom emboss die
Vector artwork of your logo or symbol (AI/EPS/PDF), the cap size (20mm) and material (standard pharmaceutical aluminum alloy), and your preferred relief style (raised or recessed). We confirm die feasibility - very fine detail or thin line elements may need simplification to emboss reliably at 20mm scale - and supply a sample cap for approval before production tooling is finalised.
Specifications:
· Size: 20mm
· Color: Yellow
· Material: Aluminum-plastic
· Service: Custom logo/words/design can be printed or not
Product Description:
1. It's better have your own design to printed as that will be exact show your idea, of course if you don't have, we can help you to do the simple design as per your idea after you order.
2. Almost our clients like to print only their pattern or only their words on flip tops, and also many cilents like mix pattern and words/comany name print on tops.
3. We can do customzied logo with embossing type and debossing type, also can make mix if possible and if you need.
4. According to our experience, if only print the pattern with a little complex such as tiger/lion head, we suggest to do the debossing type, that will be much pretty and good.
High-temp stopper & embossed cap - full specification reference
Reference specifications for the high-temperature resistant rubber stopper and custom embossed-logo 20mm crimp cap.
| Parameter | High-temp resistant stopper | Embossed 20mm crimp cap |
|---|---|---|
| Thermal performance | ||
| Rated temperature | 121°C standard · 134°C extended ★ | - |
| Cycle tolerance | Multiple autoclave cycles | - |
| Dimensional stability | Maintained through heat exposure | - |
| Material specification | ||
| Elastomer base | High-temp bromobutyl rubber | - |
| Test basis | USP <381> reference | Medical-grade aluminum alloy |
| Cap material | - | Pharmaceutical aluminum + lacquer |
| Embossing customisation | ||
| Emboss type | - | 3D raised or recessed relief ★ |
| Cap size | - | 20mm standard |
| Custom logo | - | Vector artwork → custom die |
| Combination option | - | Emboss + print colour combined |
| Compatibility & ordering | ||
| Vial compatibility | 13/20/32mm neck finish | 20mm crimp standard |
| Sample available | Yes - request free sample | Yes - sample before tooling |
| Minimum order | Confirm at enquiry | Confirm at enquiry - die tooling cost applies |
who orders this product
High-temp stoppers & embossed caps - across the pharmaceutical supply chain
High-temperature resistant rubber stoppers and custom embossed crimp caps are specified wherever terminal sterilisation and permanent brand marking are required together.
wholesale company making embossing seal
Sterile injectable manufacturers
Terminal sterilisation · autoclave
Manufacturers using terminal steam sterilisation on filled vials - requiring stoppers rated for repeated 121°C+ cycles without dimensional drift or seal degradation.
customized logo for bottles of 20mm crimp open
Vaccine & biologics producers
High-temp protocols · 20mm vial
Vaccine and biologics producers running extended or rapid sterilisation protocols on 20mm-finish vials - requiring the high-temperature resistant elastomer grade for reliable seal performance.
medical grade company making embossing flip tops
Premium peptide brands
Embossed brand mark · anti-counterfeit
Peptide brands wanting a permanent, tactile brand mark on the crimp cap that cannot wear off - using embossing as both a premium presentation feature and a passive anti-counterfeit signal.
custom logo 3D convex customized logo stamp on flip off caps
CDMOs & fill-finish
Multi-protocol · validated thermal range
Contract fill-finish organisations running multiple sterilisation protocols across client products - standardising on the high-temperature resistant grade to cover the widest thermal range without per-product stopper changes.
injectable vial top 20mm personalized with embossed words
Biotech & clinical supply
IMP · validated sterilisation cycle
Biotech clinical supply teams needing documented thermal performance data for stoppers used in validated terminal sterilisation cycles as part of regulatory submission packages.
flip tops 20mm crimp flip top custom logo cap seals
Packaging component distributors
B2B · high-temp stock · emboss service
Pharmaceutical component distributors stocking high-temperature resistant stoppers and offering custom embossing services for downstream pharmaceutical brand customers.
Heat Resistant. Permanently Branded.
Built to survive the autoclave. Embossed to last.
Request a free sample of the high-temperature resistant rubber stopper, or send your logo artwork for a custom embossed 20mm crimp cap sample. We confirm sterilisation compatibility and emboss feasibility within 48 hours.
Shipment:
By express, such as TNT, DHL, UPS, FedEx for small quantity in 5-10 working days.
By air or by sea for large quantity.
Or ship according to your request.
Order:
if you are interested in any our products (injection vials,rubber stoppers, flip top caps and so on),
It will be our honor and very pleasure to receive your inquiry,we will try our best to meet your need.
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